diff --git a/src/main/kotlin/app/revanced/patches/youtube/utils/fix/cairo/CairoSettingsPatch.kt b/src/main/kotlin/app/revanced/patches/youtube/utils/fix/cairo/CairoSettingsPatch.kt
new file mode 100644
index 000000000..c05895e50
--- /dev/null
+++ b/src/main/kotlin/app/revanced/patches/youtube/utils/fix/cairo/CairoSettingsPatch.kt
@@ -0,0 +1,46 @@
+package app.revanced.patches.youtube.utils.fix.cairo
+
+import app.revanced.patcher.data.BytecodeContext
+import app.revanced.patcher.extensions.InstructionExtensions.addInstruction
+import app.revanced.patcher.extensions.InstructionExtensions.getInstruction
+import app.revanced.patcher.patch.BytecodePatch
+import app.revanced.patcher.patch.annotation.Patch
+import app.revanced.patches.youtube.misc.minimizedplayback.MinimizedPlaybackPatch
+import app.revanced.patches.youtube.utils.fix.cairo.fingerprints.CarioFragmentConfigFingerprint
+import app.revanced.util.getTargetIndex
+import app.revanced.util.getWideLiteralInstructionIndex
+import com.android.tools.smali.dexlib2.Opcode
+import com.android.tools.smali.dexlib2.iface.instruction.OneRegisterInstruction
+
+@Patch(
+    description = "Fixes issues where Cairo Fragment is applied."
+)
+object CairoSettingsPatch : BytecodePatch(
+    setOf(CarioFragmentConfigFingerprint)
+) {
+    override fun execute(context: BytecodeContext) {
+
+        /**
+         * Cairo Fragment was added since YouTube v19.04.38.
+         * Disable this for the following reasons:
+         * 1. [MinimizedPlaybackPatch] does not activate the Minimized playback setting of Cairo Fragment.
+         * 2. Some patches implemented in RVX do not yet support Cairo Fragments.
+         *
+         * See <a href="https://github.com/inotia00/ReVanced_Extended/issues/2099">ReVanced_Extended#2099</a>
+         * or <a href="https://github.com/qnblackcat/uYouPlus/issues/1468">uYouPlus#1468</a>
+         * for screenshots of the Cairo Fragment.
+         */
+        CarioFragmentConfigFingerprint.result?.let {
+            it.mutableMethod.apply {
+                val targetIndex = getTargetIndex(getWideLiteralInstructionIndex(45532100), Opcode.MOVE_RESULT)
+                val targetRegister = getInstruction<OneRegisterInstruction>(targetIndex).registerA
+
+                addInstruction(
+                    targetIndex + 1,
+                    "const/4 v$targetRegister, 0x0"
+                )
+            }
+        }
+
+    }
+}
diff --git a/src/main/kotlin/app/revanced/patches/youtube/utils/fix/cairo/fingerprints/CarioFragmentConfigFingerprint.kt b/src/main/kotlin/app/revanced/patches/youtube/utils/fix/cairo/fingerprints/CarioFragmentConfigFingerprint.kt
new file mode 100644
index 000000000..b777e0e75
--- /dev/null
+++ b/src/main/kotlin/app/revanced/patches/youtube/utils/fix/cairo/fingerprints/CarioFragmentConfigFingerprint.kt
@@ -0,0 +1,17 @@
+package app.revanced.patches.youtube.utils.fix.cairo.fingerprints
+
+import app.revanced.patcher.extensions.or
+import app.revanced.util.fingerprint.LiteralValueFingerprint
+import com.android.tools.smali.dexlib2.AccessFlags
+
+/**
+ * Added in YouTube v19.04.38
+ *
+ * When this value is TRUE, Cairo Fragment is used.
+ * In this case, some of patches may be broken, so set this value to FALSE.
+ */
+internal object CarioFragmentConfigFingerprint : LiteralValueFingerprint(
+    returnType = "Z",
+    accessFlags = AccessFlags.PUBLIC or AccessFlags.FINAL,
+    literalSupplier = { 45532100 }
+)
\ No newline at end of file
diff --git a/src/main/kotlin/app/revanced/patches/youtube/utils/settings/SettingsPatch.kt b/src/main/kotlin/app/revanced/patches/youtube/utils/settings/SettingsPatch.kt
index fe3fd4658..c825e5b89 100644
--- a/src/main/kotlin/app/revanced/patches/youtube/utils/settings/SettingsPatch.kt
+++ b/src/main/kotlin/app/revanced/patches/youtube/utils/settings/SettingsPatch.kt
@@ -4,6 +4,7 @@ import app.revanced.patcher.data.ResourceContext
 import app.revanced.patches.shared.elements.StringsElementsUtils.removeStringsElements
 import app.revanced.patches.shared.mapping.ResourceMappingPatch
 import app.revanced.patches.youtube.utils.compatibility.Constants.COMPATIBLE_PACKAGE
+import app.revanced.patches.youtube.utils.fix.cairo.CairoSettingsPatch
 import app.revanced.patches.youtube.utils.integrations.IntegrationsPatch
 import app.revanced.patches.youtube.utils.resourceid.SharedResourceIdPatch
 import app.revanced.patches.youtube.utils.settings.ResourceUtils.addPreference
@@ -30,7 +31,8 @@ object SettingsPatch : BaseResourcePatch(
         IntegrationsPatch::class,
         ResourceMappingPatch::class,
         SharedResourceIdPatch::class,
-        SettingsBytecodePatch::class
+        SettingsBytecodePatch::class,
+        CairoSettingsPatch::class
     ),
     compatiblePackages = COMPATIBLE_PACKAGE,
     requiresIntegrations = true
@@ -46,7 +48,6 @@ object SettingsPatch : BaseResourcePatch(
     internal var upward1842 = false
     internal var upward1849 = false
     internal var upward1902 = false
-    internal var upward1909 = false
     internal var upward1912 = false
 
     override fun execute(context: ResourceContext) {
@@ -81,7 +82,6 @@ object SettingsPatch : BaseResourcePatch(
                         upward1842 = 234302000 <= playServicesVersion
                         upward1849 = 235000000 <= playServicesVersion
                         upward1902 = 240204000 < playServicesVersion
-                        upward1909 = 241002000 <= playServicesVersion
                         upward1912 = 241302000 <= playServicesVersion
 
                         break